Matrix Metalloproteinases in Chemoresistance: Regulatory Roles, Molecular Interactions, and Potential Inhibitors

• Main Authors: Tune, Bernadette Xin Jie, Sim, Maw Shin, Poh, Chit Laa *, Guad, Rhanye Mac, Woon, Choy Ker, Hazarika, Iswar, Das, Anju, Gopinath, Subash C B, Rajan, Mariappan, Mahendran, Sekar, Vetriselvan, Subramaniyan, Fuloria, Neeraj Kumar, Fuloria, Shivkanya, Kalaivani, Batumalaie, Wu, Yuan Seng *
• Format: Article
• Language: English
• Published: Wiley Open Access 2022
• Subjects: RC Internal medicine; RM Therapeutics. Pharmacology
• Online Access: http://eprints.sunway.edu.my/2992/1/Wu%20Yuan%20Seng_Matrix%20metalloproteinases%20in%20chemoresistance.pdf; http://eprints.sunway.edu.my/2992/; https://doi.org/10.1155/2022/3249766
• Institution: Sunway University

Cancer is one of the major causes of death worldwide. Its treatments usually fail when the tumor has become malignant and metastasized. Metastasis is a key source of cancer recurrence, which often leads to resistance towards chemotherapeutic agents. Hence, most cancer-related deaths are linked to th...