Cross-Neutralizing CRF01-AE-Infected Plasma from Malaysia Targets CD4-Binding Site of Human Immunodeficiency Virus Type-1 Envelope Glycoprotein

• Main Authors: Ng, Qi Ron *, Tee, Kok Keng, Binley, James M, Tong, Tommy *
• Format: Article
• Published: Mary Ann Liebert 2022
• Subjects: QR Microbiology; RA Public aspects of medicine; RC Internal medicine
• Online Access: http://eprints.sunway.edu.my/3022/; https://doi.org/10.1089/aid.2020.0299
• Institution: Sunway University

Human immunodeficiency virus type-1 (HIV-1) antigenic variation poses a great challenge for vaccine immunogen design to elicit broadly neutralizing antibodies (bNAbs). Over the last 10-15 years, great progress has been made to understand the conserved sites of sensitivity on HIV envelope glycoprotei...