Prediction of Low-Dose Aspirin-Induced Gastric Toxicity Using Nuclear Magnetic Resonance Spectroscopy-Based Pharmacometabolomics in Rats

Prediction of Low-Dose Aspirin-Induced Gastric Toxicity Using Nuclear Magnetic Resonance Spectroscopy-Based Pharmacometabolomics in Rats

Background: Low-dose aspirin (LDA) is the backbone for secondary prevention of coronary artery disease, although limited by gastric toxicity. This study aimed to identify novel metabolites that could predict LDA-induced gastric toxicity using pharmacometabolomics. Methods: Pre-dosed urine samples...

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Main Authors: Abubakar, Sha'aban, Hadzliana, Zainal, Nor Azlina, Khalil, Fatimatuzzahra', Abd Aziz, Ch'ng, Ewe Seng *, Teh, Chin Hoe, Mustapha, Mohammed, Baharudin, Ibrahim
Format: Article
Published: MDPI 2022
Subjects:
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:http://eprints.sunway.edu.my/3040/
https://doi.org/10.3390/molecules27072126
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Institution: Sunway University

Internet

http://eprints.sunway.edu.my/3040/
https://doi.org/10.3390/molecules27072126

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