Potential anti-acanthamoebic effects through inhibition of CYP51 by novel quinazolinones

Potential anti-acanthamoebic effects through inhibition of CYP51 by novel quinazolinones

Acanthamoeba spp. are free living amoebae which can give rise to Acanthamoeba keratitis and granulomatous amoebic encephalitis. The surface of Acanthamoeba contains ergosterol which is an important target for drug development against eukaryotic microorganisms. A library of ten functionally diverse q...

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Main Authors: Usman, Ahmed *, Ho, Keat Yie, Simon, Samson Eugin *, Saad, Syed Muhammad, Ong, Seng Kai *, Areeba, Anwar, Tan, Kuan Onn *, Nanthini, Sridewi, Khan, Khalid Mohammed, Khan, Naveed Ahmed, Ayaz, Anwar *
Format: Article
Published: Elsevier 2022
Subjects:
QL Zoology
RM Therapeutics. Pharmacology
Online Access:http://eprints.sunway.edu.my/3115/
https://doi.org/10.1016/j.actatropica.2022.106440
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Institution: Sunway University

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http://eprints.sunway.edu.my/3115/
https://doi.org/10.1016/j.actatropica.2022.106440

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