Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease.

Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease.

Boesenbergia rotunda (L.) cyclohexenyl chalcone derivatives, 4-hydroxypanduratin A and panduratin A, showed good competitive inhibitory activities towards dengue 2 virus NS3 protease with the Ki values of 21 and 25 microM, respectively, whilst those of pinostrobin and cardamonin were observed to be...

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Bibliographic Details
Main Authors: Tan, Siew Kiat *, Pippen, Richard, Rohana Yusof, Halijah Ibrahim, Norzulaani Khalid, Noorsaadah Abd Rahman
Format: Article
Published: Elsevier Ltd 2006
Subjects:
QK Botany
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:http://eprints.sunway.edu.my/32/
http://dx.doi.org/10.1016/j.bmcl.2005.12.075
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Institution: Sunway University

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http://eprints.sunway.edu.my/32/
http://dx.doi.org/10.1016/j.bmcl.2005.12.075

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