Mechanism of folate metabolism: methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms in Malaysian mothers with down syndrome children / Maziana Mahamood, Prof. Dr. Aishah Adam and Mizaton Hazizul Hasan

• Main Authors: Mahamood, Maziana, Adam, Aishah, Hazizul Hasan, Mizaton
• 格式: Research Reports
• 語言: English
• 出版: Institut Teknologi MARA 2016
• 在線閱讀: https://ir.uitm.edu.my/id/eprint/13785/2/13785.pdf; https://ir.uitm.edu.my/id/eprint/13785/
• 機構: Universiti Teknologi Mara

Trisomy 21 (Down syndrome, DS) is a common chromosomal abnormality occuring in about 1 in 700 live births. Studies to date have found the relationship between folate metabolism and chromosomal nondisjunction. Folate metabolic pathways involve many genes and one of that is methylenetetrahydrofolate r...