Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan

Vitex triflolia is one of the Vitex species where known as Lemuni. It is widely used traditionally to reduce pain, fever and minor ailments. Every part of the plant had its advantages; for example, the leaves part can relieve pain, treat fever and can help to improve memory. It has potent pharmacolo...

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Main Authors: Mohd Shukri, Nur Afifah, Hasan, Mizaton Hazizul
Format: Article
Language:English
Published: Faculty of Pharmacy 2021
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/70698/2/70698.pdf
https://ir.uitm.edu.my/id/eprint/70698/
http://ijpncs.uitm.edu.my/index.php/en/ijpncs-journal
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Institution: Universiti Teknologi Mara
Language: English
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spelling my.uitm.ir.706982024-05-23T08:17:53Z https://ir.uitm.edu.my/id/eprint/70698/ Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan ijpnacs Mohd Shukri, Nur Afifah Hasan, Mizaton Hazizul Angiosperms Antioxidants Drugs and their actions Vitex triflolia is one of the Vitex species where known as Lemuni. It is widely used traditionally to reduce pain, fever and minor ailments. Every part of the plant had its advantages; for example, the leaves part can relieve pain, treat fever and can help to improve memory. It has potent pharmacological activities such as antioxidant, antinociceptive, anti-inflammatory and anticancer. Other than that, every part of the plant has unique constituents with different biological activities. A few isolated and identified flavonoids in V. trifolia include casticin, persinogenin, artemetin, luteolin, penduletin, vitexicarpin and chrysisplenol. These flavonoids can inhibit the cell cycle involved in carcinogenesis and have been reported to have antiinflammatory properties. In putting together this review, PRISMA was adopted, which utilised two primary journal databases, Scopus and PubMed and a supporting database, Google Scholar. The search resulted in 17 journals for this review that covered the phytochemical constituents and pharmacological activities of V. trifolia. To conclude, this review provided insightful information on how the knowledge gap on V. trifolia can be exploited as possible treatments for COVID-19 as the extracts have shown potential anticancer, anti-inflammatory, antioxidant and other pharmacological properties due to the presence of the phytochemical constituents in the plant. Faculty of Pharmacy 2021 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/70698/2/70698.pdf Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan. (2021) International Journal of Pharmaceuticals, Nutraceuticals and Cosmetic Science (IJPNaCS) <https://ir.uitm.edu.my/view/publication/International_Journal_of_Pharmaceuticals,_Nutraceuticals_and_Cosmetic_Science_=28IJPNaCS=29/>, 3. pp. 49-65. ISSN 2682-8146 http://ijpncs.uitm.edu.my/index.php/en/ijpncs-journal
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Angiosperms
Antioxidants
Drugs and their actions
spellingShingle Angiosperms
Antioxidants
Drugs and their actions
Mohd Shukri, Nur Afifah
Hasan, Mizaton Hazizul
Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan
description Vitex triflolia is one of the Vitex species where known as Lemuni. It is widely used traditionally to reduce pain, fever and minor ailments. Every part of the plant had its advantages; for example, the leaves part can relieve pain, treat fever and can help to improve memory. It has potent pharmacological activities such as antioxidant, antinociceptive, anti-inflammatory and anticancer. Other than that, every part of the plant has unique constituents with different biological activities. A few isolated and identified flavonoids in V. trifolia include casticin, persinogenin, artemetin, luteolin, penduletin, vitexicarpin and chrysisplenol. These flavonoids can inhibit the cell cycle involved in carcinogenesis and have been reported to have antiinflammatory properties. In putting together this review, PRISMA was adopted, which utilised two primary journal databases, Scopus and PubMed and a supporting database, Google Scholar. The search resulted in 17 journals for this review that covered the phytochemical constituents and pharmacological activities of V. trifolia. To conclude, this review provided insightful information on how the knowledge gap on V. trifolia can be exploited as possible treatments for COVID-19 as the extracts have shown potential anticancer, anti-inflammatory, antioxidant and other pharmacological properties due to the presence of the phytochemical constituents in the plant.
format Article
author Mohd Shukri, Nur Afifah
Hasan, Mizaton Hazizul
author_facet Mohd Shukri, Nur Afifah
Hasan, Mizaton Hazizul
author_sort Mohd Shukri, Nur Afifah
title Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan
title_short Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan
title_full Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan
title_fullStr Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan
title_full_unstemmed Pharmacological review of Vitex trifolia / Nur Afifah Mohd Shukri and Mizaton Hazizul Hasan
title_sort pharmacological review of vitex trifolia / nur afifah mohd shukri and mizaton hazizul hasan
publisher Faculty of Pharmacy
publishDate 2021
url https://ir.uitm.edu.my/id/eprint/70698/2/70698.pdf
https://ir.uitm.edu.my/id/eprint/70698/
http://ijpncs.uitm.edu.my/index.php/en/ijpncs-journal
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