Hypothalamic mediation of reduced GH secretion in diabetic rats: evidence for reduced cholinergic inhibition of somatostatin release

• المؤلفون الرئيسيون: Ismail, I.S., Lewis, M., Peters, J.R., Scanlon, M.F.
• التنسيق: مقال
• اللغة: English
• منشور في: Blackwell Publishing 1995
• الموضوعات: R Medicine (General)
• الوصول للمادة أونلاين: http://eprints.um.edu.my/10398/1/Hypothalamic.pdf; http://eprints.um.edu.my/10398/
• المؤسسة: Universiti Malaya

The Goto-Kakizaki (GK) rat is a new model of diabetes mellitus and in this study we have characterized the diabetic and growth hormone (GH) secretory status of male GK rats at 6 and 16 weeks of age. We have also investigated the role of endogenous somatostatin (SS) and cholinergic manipulation on th...