Acute cholinergic blockade with low dose pirenzepine reduces the insulin and glucose responses to a mixed meal in obese women with the polycystic ovary syndrome

• Main Authors: Ismail, I.S., Premawardhana, L.D.K.E., Riad-Fahmy, D., Miell, J.P., Peters, J.R., Scanlon, M.F.
• Format: Article
• Language: English
• Published: Wiley 1994
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/10410/1/Acute_cholinergic_blockade_with_low_dose_pirenzepine.pdf; http://eprints.um.edu.my/10410/
• Institution: Universiti Malaya

Pirenzepine, a selective muscarinic cholinergic antagonist, reduces plasma insulin and plasma glucose responses to a mixed meal in a dose dependent fashion in normals and in patients with non-insulin dependent diabetes. We have studied the effects of pirenzepine on plasma insulin, plasma glucose, gr...