In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis

In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis

Ribotyping, PCR-ribotyping and pulsed-field gel electrophoresis were used to analyze five serial isolates of Salmonella typhi obtained from a single patient with relapsing typhoid fever over a 7-week period. The 5 isolates were genetically identical by all three methods thus suggesting relapsing inf...

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Main Authors: Thong, Kwai Lin, Puthucheary, S.D., Pang, T.
Format: Article
Language:English
Published: 1995
Subjects:
QR Microbiology
Online Access:http://eprints.um.edu.my/10423/1/Thong_et_al.%2C_1995.pdf
http://eprints.um.edu.my/10423/
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Institution: Universiti Malaya
Language: English
id my.um.eprints.10423
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spelling my.um.eprints.104232018-10-12T06:27:09Z http://eprints.um.edu.my/10423/ In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis Thong, Kwai Lin Puthucheary, S.D. Pang, T. QR Microbiology Ribotyping, PCR-ribotyping and pulsed-field gel electrophoresis were used to analyze five serial isolates of Salmonella typhi obtained from a single patient with relapsing typhoid fever over a 7-week period. The 5 isolates were genetically identical by all three methods thus suggesting relapsing infection with the same strain and implying in vivo genomic stability of S. typhi even in the presence of selective pressures of antibiotic treatment and host defenses. 1995 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10423/1/Thong_et_al.%2C_1995.pdf Thong, Kwai Lin and Puthucheary, S.D. and Pang, T. (1995) In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis. Asia Pacific Journal of Molecular Biology and Biotechnology, 3 (4). pp. 356-361.
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic QR Microbiology
spellingShingle QR Microbiology
Thong, Kwai Lin
Puthucheary, S.D.
Pang, T.
In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis
description Ribotyping, PCR-ribotyping and pulsed-field gel electrophoresis were used to analyze five serial isolates of Salmonella typhi obtained from a single patient with relapsing typhoid fever over a 7-week period. The 5 isolates were genetically identical by all three methods thus suggesting relapsing infection with the same strain and implying in vivo genomic stability of S. typhi even in the presence of selective pressures of antibiotic treatment and host defenses.
format Article
author Thong, Kwai Lin
Puthucheary, S.D.
Pang, T.
author_facet Thong, Kwai Lin
Puthucheary, S.D.
Pang, T.
author_sort Thong, Kwai Lin
title In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis
title_short In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis
title_full In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis
title_fullStr In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis
title_full_unstemmed In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis
title_sort in vivo genetic stability of salmonella typhi detected by ribotyping and pulsed field gel electrophoresis
publishDate 1995
url http://eprints.um.edu.my/10423/1/Thong_et_al.%2C_1995.pdf
http://eprints.um.edu.my/10423/
_version_ 1643688795621556224

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