A schiff base-derived copper (II) complex is a potent inducer of apoptosis in colon cancer cells by activating the intrinsic pathway

• Main Authors: Hajrezaie, M., Paydar, M., Moghadamtousi, S.Z., Hassandarvish, P., Gwaram, N.S., Zahedifard, M., Rouhollah, E., Karimian, H., Looi, C.Y., Ali, H.M., Majid, N.A., Abdulla, M.A.
• Format: Article
• Language: English
• Published: Hindawi Publishing Corporation 2014
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/10529/1/A_Schiff_Base-Derived_Copper_%28II%29_Complex_Is.pdf; http://eprints.um.edu.my/10529/
• Institution: Universiti Malaya

Metal-based drugs with extensive clinical applications hold great promise for the development of cancer chemotherapeutic agents. In the last few decades, Schiff bases and their complexes have become well known for their extensive biological potential. In the present study, we examined the antiprolif...