Indole-7-carbaldehyde thiosemicarbazone as a flexidentate ligand toward ZnII, CdII, PdII and PtII ions: cytotoxic and apoptosis-inducing properties of the PtII complex

• Main Authors: Ibrahim, A.A., Khaledi, H., Hassandarvish, P., Ali, H.M., Karimian, H.
• Format: Article
• Language: English
• Published: Royal Society of Chemistry 2014
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/10566/1/Indole-7-carbaldehyde_thiosemicarbazone_as_a_flexidentate_ligand_toward.pdf; http://eprints.um.edu.my/10566/
• Institution: Universiti Malaya

A new thiosemicarbazone (LH2) derived from indole-7-carbaldehyde was synthesized and reacted with Zn(II), Cd(II), Pd(II) and Pt(II) salts. The reactions with zinc and cadmium salts in 2 : 1 (ligand-metal) molar ratio afforded complexes of the type MX2(LH2)2, (X = Cl, Br or OAc), in which the thiosem...