Lack of clinical manifestations in asymptomatic dengue infection is attributed to broad down-regulation and selective up-regulation of host defence response genes

• Main Authors: Yeo, A.S.L., Azhar, N.A., Yeow, W., Talbot Jr, C.C., Khan, M.A., Shankar, E.M., Rathakrishnan, A., Azizan, A., Wang, S.M., Lee, S.K., Manikam, R.
• Format: Article
• Language: English
• Published: Public Library of Science 2014
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/10620/1/Yeo-2014-Lack_of_Clinical_Man.pdf; http://eprints.um.edu.my/10620/
• Institution: Universiti Malaya

Objectives Dengue represents one of the most serious life-threatening vector-borne infectious diseases that afflicts approximately 50 million people across the globe annually. Whilst symptomatic infections are frequently reported, asymptomatic dengue remains largely unnoticed. Therefore, we sought t...