Imatinib resistance and blast transformation of chronic myeloid leukemia associated with a novel tri-nucleotide insertion mutation of BCR-ABL kinase domain at position K294

Imatinib resistance and blast transformation of chronic myeloid leukemia associated with a novel tri-nucleotide insertion mutation of BCR-ABL kinase domain at position K294

A letter to the editor is presented which discusses the introduction of imatinib mesylate (IM) in the medical case of an 18-year old man with in-frame mutations and blast transformation of chronic myeloid leukemia (CML).

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Bibliographic Details
Main Authors: Nadarajan, V.S., Ang, C.H., Syed-Sultan, M.K., Bee, P.C.
Format: Article
Published: Springer Verlag (Germany) 2012
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/12027/
http://link.springer.com/article/10.1007%2Fs00277-011-1215-2
http://dx.doi.org/10.1007/s00277-011-1215-2
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Institution: Universiti Malaya

Internet

http://eprints.um.edu.my/12027/
http://link.springer.com/article/10.1007%2Fs00277-011-1215-2
http://dx.doi.org/10.1007/s00277-011-1215-2

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