Bisnicalaterines B and C, atropisomeric bisindole alkaloids from hunteria zeylanica, showing vasorelaxant activity

• Main Authors: Hirasawa, Y., Hara, M., Nugroho, A.E., Sugai, M., Zaima, K., Kawahara, N., Goda, Y., Awang, K., Hadi, A.H.A., Litaudon, M., Morita, H.
• Format: Article
• Published: American Chemical Society 2010
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/13222/
• Institution: Universiti Malaya

Two new bisindole alkaloids, bisnicalaterines B and C (1 and 2) consisting of an eburnane and a corynanthe type of skeletons, were isolated from the bark of Hunteria zeylanica. Their absolute structures were determined by combination of NMR, CD, and computational methods, and each of them was shown...