Complement-opsonized HIV-1 alters cross talk between dendritic cells and natural killer (NK) cells to inhibit NK killing and to upregulate PD-1, CXCR3, and CCR4 on T cells

Complement-opsonized HIV-1 alters cross talk between dendritic cells and natural killer (NK) cells to inhibit NK killing and to upregulate PD-1, CXCR3, and CCR4 on T cells

Dendritic cells (DCs), natural killer (NK) cells, and T cells play critical roles during primary HIV-1 exposure at the mucosa, where the viral particles become coated with complement fragments and mucosa-associated antibodies. The microenvironment together with subsequent interactions between these...

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Main Authors: Ellegard, Rada, Khalid, Mohammad, Svanberg, Cecilia, Holgersson, Hanna, Thorén, Ylva, Wittgren, Mirja Karolina, Hinkula, Jorma, Nyström, Sofia, Shankar, Esaki Muthu, Larsson, Marie
Format: Article
Published: Frontiers Media 2010
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/14213/
https://doi.org/10.3389/fimmu.2018.00899
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Institution: Universiti Malaya

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http://eprints.um.edu.my/14213/
https://doi.org/10.3389/fimmu.2018.00899

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