Efficient one-pot synthesis of 2,2-dimethyl-2H-chromenes via pd(II)-catalyzed coupling and SiO2-promoted condensation of o-halophenols with 2-methyl-3-buten-2-ol

An efficient synthesis of 2,2-dimethyl-2H-chromenes was accomplished by Pd(II)-catalyzed coupling and SiO2-promoted condensation of o-halophenols with 2-methyl-3-buten-2-ol (1,1-dimethylallyl alcohol) in one pot. The method is very general and can be useful for the synthesis of some natural 2,2-dime...

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Bibliographic Details
Main Authors: Tee, Jia Ti, Yaeghoobi, Marzieh, Chee, Chin Fei, Abd Rahman, Noorsaadah
Format: Article
Published: Taylor & Francis 2015
Subjects:
Online Access:http://eprints.um.edu.my/14606/
http://www.tandfonline.com/doi/abs/10.1080/00397911.2015.1056371
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Institution: Universiti Malaya
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Summary:An efficient synthesis of 2,2-dimethyl-2H-chromenes was accomplished by Pd(II)-catalyzed coupling and SiO2-promoted condensation of o-halophenols with 2-methyl-3-buten-2-ol (1,1-dimethylallyl alcohol) in one pot. The method is very general and can be useful for the synthesis of some natural 2,2-dimethyl-2H-chromenes.