Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
Background and Aim: The contribution of human genetic polymorphisms to Helicobacter pylori infection and gastric cancer (GC) development remains unclear due to geographic variation in the association between specific host genetic polymorphisms and GC. In the current study we investigated the associa...
Saved in:
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Published: |
Blackwell Publishing
2010
|
Subjects: | |
Online Access: | http://eprints.um.edu.my/14689/ |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Universiti Malaya |
id |
my.um.eprints.14689 |
---|---|
record_format |
eprints |
spelling |
my.um.eprints.146892015-11-09T01:33:08Z http://eprints.um.edu.my/14689/ Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country Schmidt, Heather-Marie.A. Ha, D.M. Taylor, E.F. Kovach, Z. Goh, Khean-Lee Fock, K.M. Barrett, J.H. Forman, D. Mitchell, H. Q Science (General) Background and Aim: The contribution of human genetic polymorphisms to Helicobacter pylori infection and gastric cancer (GC) development remains unclear due to geographic variation in the association between specific host genetic polymorphisms and GC. In the current study we investigated the association between polymorphisms related to immune and cancer-related pathways and H. pylori infection among the major ethnicities, Chinese, Malay and Indian, resident in Singapore and Malaysia as well as the association between these polymorphisms and GC development in ethnic Chinese patients. Blackwell Publishing 2010 Article PeerReviewed Schmidt, Heather-Marie.A. and Ha, D.M. and Taylor, E.F. and Kovach, Z. and Goh, Khean-Lee and Fock, K.M. and Barrett, J.H. and Forman, D. and Mitchell, H. (2010) Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country. Journal of Gastroenterology and Hepatology, 26 (12). pp. 1725-1732. |
institution |
Universiti Malaya |
building |
UM Library |
collection |
Institutional Repository |
continent |
Asia |
country |
Malaysia |
content_provider |
Universiti Malaya |
content_source |
UM Research Repository |
url_provider |
http://eprints.um.edu.my/ |
topic |
Q Science (General) |
spellingShingle |
Q Science (General) Schmidt, Heather-Marie.A. Ha, D.M. Taylor, E.F. Kovach, Z. Goh, Khean-Lee Fock, K.M. Barrett, J.H. Forman, D. Mitchell, H. Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country |
description |
Background and Aim: The contribution of human genetic polymorphisms to Helicobacter pylori infection and gastric cancer (GC) development remains unclear due to geographic variation in the association between specific host genetic polymorphisms and GC. In the current study we investigated the association between polymorphisms related to immune and cancer-related pathways and H. pylori infection among the major ethnicities, Chinese, Malay and Indian, resident in Singapore and Malaysia as well as the association between these polymorphisms and GC development in ethnic Chinese patients. |
format |
Article |
author |
Schmidt, Heather-Marie.A. Ha, D.M. Taylor, E.F. Kovach, Z. Goh, Khean-Lee Fock, K.M. Barrett, J.H. Forman, D. Mitchell, H. |
author_facet |
Schmidt, Heather-Marie.A. Ha, D.M. Taylor, E.F. Kovach, Z. Goh, Khean-Lee Fock, K.M. Barrett, J.H. Forman, D. Mitchell, H. |
author_sort |
Schmidt, Heather-Marie.A. |
title |
Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country |
title_short |
Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country |
title_full |
Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country |
title_fullStr |
Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country |
title_full_unstemmed |
Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country |
title_sort |
variation in human genetic polymorphisms, their association with helicobacter pylori acquisition and gastric cancer in a multi-ethnic country |
publisher |
Blackwell Publishing |
publishDate |
2010 |
url |
http://eprints.um.edu.my/14689/ |
_version_ |
1643689877847408640 |