Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country

Background and Aim: The contribution of human genetic polymorphisms to Helicobacter pylori infection and gastric cancer (GC) development remains unclear due to geographic variation in the association between specific host genetic polymorphisms and GC. In the current study we investigated the associa...

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Main Authors: Schmidt, Heather-Marie.A., Ha, D.M., Taylor, E.F., Kovach, Z., Goh, Khean-Lee, Fock, K.M., Barrett, J.H., Forman, D., Mitchell, H.
Format: Article
Published: Blackwell Publishing 2010
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Online Access:http://eprints.um.edu.my/14689/
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spelling my.um.eprints.146892015-11-09T01:33:08Z http://eprints.um.edu.my/14689/ Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country Schmidt, Heather-Marie.A. Ha, D.M. Taylor, E.F. Kovach, Z. Goh, Khean-Lee Fock, K.M. Barrett, J.H. Forman, D. Mitchell, H. Q Science (General) Background and Aim: The contribution of human genetic polymorphisms to Helicobacter pylori infection and gastric cancer (GC) development remains unclear due to geographic variation in the association between specific host genetic polymorphisms and GC. In the current study we investigated the association between polymorphisms related to immune and cancer-related pathways and H. pylori infection among the major ethnicities, Chinese, Malay and Indian, resident in Singapore and Malaysia as well as the association between these polymorphisms and GC development in ethnic Chinese patients. Blackwell Publishing 2010 Article PeerReviewed Schmidt, Heather-Marie.A. and Ha, D.M. and Taylor, E.F. and Kovach, Z. and Goh, Khean-Lee and Fock, K.M. and Barrett, J.H. and Forman, D. and Mitchell, H. (2010) Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country. Journal of Gastroenterology and Hepatology, 26 (12). pp. 1725-1732.
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
spellingShingle Q Science (General)
Schmidt, Heather-Marie.A.
Ha, D.M.
Taylor, E.F.
Kovach, Z.
Goh, Khean-Lee
Fock, K.M.
Barrett, J.H.
Forman, D.
Mitchell, H.
Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
description Background and Aim: The contribution of human genetic polymorphisms to Helicobacter pylori infection and gastric cancer (GC) development remains unclear due to geographic variation in the association between specific host genetic polymorphisms and GC. In the current study we investigated the association between polymorphisms related to immune and cancer-related pathways and H. pylori infection among the major ethnicities, Chinese, Malay and Indian, resident in Singapore and Malaysia as well as the association between these polymorphisms and GC development in ethnic Chinese patients.
format Article
author Schmidt, Heather-Marie.A.
Ha, D.M.
Taylor, E.F.
Kovach, Z.
Goh, Khean-Lee
Fock, K.M.
Barrett, J.H.
Forman, D.
Mitchell, H.
author_facet Schmidt, Heather-Marie.A.
Ha, D.M.
Taylor, E.F.
Kovach, Z.
Goh, Khean-Lee
Fock, K.M.
Barrett, J.H.
Forman, D.
Mitchell, H.
author_sort Schmidt, Heather-Marie.A.
title Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
title_short Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
title_full Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
title_fullStr Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
title_full_unstemmed Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
title_sort variation in human genetic polymorphisms, their association with helicobacter pylori acquisition and gastric cancer in a multi-ethnic country
publisher Blackwell Publishing
publishDate 2010
url http://eprints.um.edu.my/14689/
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