Experimental infection of squirrel monkeys with nipah virus

Experimental infection of squirrel monkeys with nipah virus

We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous infection was followed by high death rates associat...

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Bibliographic Details
Main Authors: Marianneau, P., Guillaume, V., Wong, K.T., Badmanathan, M., Looi, R.Y., Murri, S., Loth, P., Tordo, N., Wild, T.F., Horvat, B., Contamin, H.
Format: Article
Published: Centers Disease Control 2010
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/15128/
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Institution: Universiti Malaya
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Summary:We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous infection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.

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