Cyclisation of 1,2-dioxines containing tethered hydroxyl and carboxylic acid functionality: Synthesis of tetrahydrofurans and dihydrofuran-2(3H)-ones

Herein we outline cyclisations of tethered hydroxyl and carboxylic acid moieties onto the olefinic motif of 1,2-dioxines to generate tetrahydrofurans and dihydrofuran-2(3H)-ones, whilst maintaining the peroxide linkage intact. This work demonstrates the first examples of intramolecular cyclisation o...

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Bibliographic Details
Main Authors: Zvarec, O., Avery, T.D., Taylor, D.K., Tiekink, E.R.T.
Format: Article
Published: Elsevier 2010
Subjects:
Online Access:http://eprints.um.edu.my/15263/
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Institution: Universiti Malaya