The impact of antibody/epitope affinity strength on the sensitivity of electrochemical immunosensors for detecting small molecules
A displacement immunoassay involves having a labelled analogue of the analyte (the epitope) already bound to the antibody. The presence of the analyte causes a competition for antibodies, and some of the antibodies dissociates from the epitope so that it can bind with the analyte. Herein, the i...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Verlag (Germany)
2013
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/15519/1/Analytical_and_Bioanalytical_Chemistry_405%282013%293889-3898_%28post-print_version%29.pdf http://eprints.um.edu.my/15519/ http://dx.doi.org/10.1007/s00216-013-6782-8 http://download.springer.com/static/pdf/674/art253A10.1007252Fs00216-013-6782-8.pdf?originUrl=http3A2F2Flink.springer.com2Farticle2F10.10072Fs00216-013-6782-8&token2=exp=1450677127~acl=2Fstatic2Fpdf2F6742Fart252 |
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| Institution: | Universiti Malaya |
| Language: | English |
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http://eprints.um.edu.my/15519/1/Analytical_and_Bioanalytical_Chemistry_405%282013%293889-3898_%28post-print_version%29.pdfhttp://eprints.um.edu.my/15519/
http://dx.doi.org/10.1007/s00216-013-6782-8 http://download.springer.com/static/pdf/674/art253A10.1007252Fs00216-013-6782-8.pdf?originUrl=http3A2F2Flink.springer.com2Farticle2F10.10072Fs00216-013-6782-8&token2=exp=1450677127~acl=2Fstatic2Fpdf2F6742Fart252