Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma

In this study, we first performed whole exome sequencing of DNA from 10 untreated and clinically annotated fresh frozen nasopharyngeal carcinoma (NPC) biopsies and matched bloods to identify somatically mutated genes that may be amenable to targeted therapeutic strategies. We identified a total of 3...

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Bibliographic Details
Main Authors: Chow, Y.P., Tan, L.P., Chai, S.J., Abdul Aziz, N., Choo, S.W., Lim, P.V.H., Pathmanathan, R., Mohd Kornain, N.K., Lum, C.L., Pua, K.C., Yap, Y.Y., Tan, T.Y., Teo, S.H., Khoo, A.S.B., Patel, V.
Format: Article
Language:English
Published: Nature Publishing Group 2017
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Online Access:http://eprints.um.edu.my/17153/1/srep42980_%281%29.pdf
http://eprints.um.edu.my/17153/
https://www.nature.com/articles/srep42980
https://doi.org/10.1038/srep42980
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Institution: Universiti Malaya
Language: English