Regions of very low H3K27me3 partition the Drosophila genome into topological domains

• Main Authors: El-Sharnouby, S., Fischer, B., Magbanua, J.P., Umans, B., Flower, R., Choo, S.W., Russell, S., White, R.
• Format: Article
• Language: English
• Published: Public Library of Science 2017
• Subjects: Practice of dentistry. Dental economics
• Online Access: http://eprints.um.edu.my/17154/1/journal.pone.0172725.pdf; http://eprints.um.edu.my/17154/; http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172725; https://doi.org/10.1371/journal.pone.0172725
• Institution: Universiti Malaya

It is now well established that eukaryote genomes have a common architectural organization into topologically associated domains (TADs) and evidence is accumulating that this organization plays an important role in gene regulation. However, the mechanisms that partition the genome into TADs and the...