Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia
We report herein the clinical presentation and diagnosis of scrub typhus in three patients attending a teaching hospital in Malaysia. Three genetic variants belonged to the Karp and Gilliam strains of O. tsutsugamushi were amplified from the acute blood samples of the patients by a nested polymerase...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Malaysian Society for Parasitology
2016
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/18313/ https://drive.google.com/file/d/0B75lcx0mfp2OZGdoYW1qV2syaGc/view |
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| Institution: | Universiti Malaya |
| Summary: | We report herein the clinical presentation and diagnosis of scrub typhus in three patients attending a teaching hospital in Malaysia. Three genetic variants belonged to the Karp and Gilliam strains of O. tsutsugamushi were amplified from the acute blood samples of the patients by a nested polymerase chain reaction assay. The circulation of different genetic variants of O. tsutsugamushi strains might complicate the presentation and severity of scrub typhus. Loop-PCR is a promising diagnostic tool for rapid diagnosis of scrub typhus. |
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