New insights into the mode of action of the lantibiotic salivaricin B

• Main Authors: Barbour, A., Tagg, J., Abou-Zied, O.K., Philip, K.
• Format: Article
• Published: Nature Publishing Group 2016
• Subjects: Q Science (General); QH Natural history
• Online Access: http://eprints.um.edu.my/18465/; https://doi.org/10.1038/srep31749
• Institution: Universiti Malaya

Salivaricin B is a 25 amino acid polycyclic peptide belonging to the type AII lantibiotics and first shown to be produced by Streptococcus salivarius. In this study we describe the bactericidal mode of action of salivaricin B against susceptible Gram-positive bacteria. The killing action of salivari...