Withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation
Activation of inflammatory pathways via reactive oxygen species (ROS) by free fatty acids (FFA) in obesity gives rise to insulin resistance and endothelial dysfunction. Withaferin A (WA), possesses both antioxidant and anti-inflammatory properties and therefore would be a good strategy to suppress p...
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Main Authors: | , , , , |
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Format: | Article |
Published: |
Nature Publishing Group
2016
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Subjects: | |
Online Access: | http://eprints.um.edu.my/18488/ http://dx.doi.org/10.1038/srep27236 |
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Institution: | Universiti Malaya |