Oral immunization of a non-recombinant Lactococcus lactis surface displaying influenza hemagglutinin 1 (HA1) induces mucosal immunity in mice

• Main Authors: Jee, P.F., Tiong, V., Shu, M.H., Khoo, J.J., Wong, W.F., Rahim, R.A., AbuBakar, Sazaly, Chang, L.Y.
• Format: Article
• Published: Public Library of Science 2017
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/19154/; http://dx.doi.org/10.1371/journal.pone.0187718
• Institution: Universiti Malaya

Mucosal immunization of influenza vaccine is potentially an effective approach for the prevention and control of influenza. The objective of the present study was to evaluate the ability of oral immunization with a non-recombinant Lactococcus lactis displaying HA1/L/AcmA recombinant protein, LL-HA1/...