Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study

Background: Acute otitis media (AOM) affects both child and parental quality of life (QoL). Data on QoL associated with AOM in Malaysia is sparse, and the burden of indirect costs have not been previously reported. Objective: To determine the effect of pediatric AOM on child and parental QoL in Mala...

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Main Authors: Crawford, Bruce, Hashim, Siti Sabzah Mohd, Prepageran, Narayanan, Goh, Bee See, Meier, Genevieve, Wada, Keiko, Coon, Cheryl, Delgleize, Emmanuelle, DeRosa, Michael
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Published: Adis Open Access 2017
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Online Access:http://eprints.um.edu.my/19198/
http://dx.doi.org/10.1007/s40801-016-0099-9
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spelling my.um.eprints.191982018-10-24T03:07:00Z http://eprints.um.edu.my/19198/ Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study Crawford, Bruce Hashim, Siti Sabzah Mohd Prepageran, Narayanan Goh, Bee See Meier, Genevieve Wada, Keiko Coon, Cheryl Delgleize, Emmanuelle DeRosa, Michael R Medicine Background: Acute otitis media (AOM) affects both child and parental quality of life (QoL). Data on QoL associated with AOM in Malaysia is sparse, and the burden of indirect costs have not been previously reported. Objective: To determine the effect of pediatric AOM on child and parental QoL in Malaysia and its economic impact (indirect costs). Methods: We utilized a set of QoL questionnaires (PAR-AOM-QOL, OM-6, and EQ-5D) combined with questions addressing work/productivity loss and financial costs associated with caring for a child during his or her illness in an observational, multicenter, prospective study. Results: One hundred and ten AOM patients aged ≤5 years were included in the analysis. The majority of respondents were the patient’s mother. Parental QoL was negatively affected for both emotional and daily disturbance scales, but the level of disturbance was low. Using OM-6, the greatest negative impact was on the child’s QoL, followed by caregiver concerns, physical suffering, and emotional distress. Using EQ-5D, a moderately positive relationship between parents’ emotional disturbance and daily disturbance, and a weak, negative correlation between parental emotional disturbance and parental health status was found. Parents with paid employment took an average of 21 h from work to care for their child, at an average cost of 321.8 Malaysian ringgit (US$97) in addition to their contribution to direct medical costs. Productivity losses whilst at work, uncompensated wage losses, and leisure time losses are also reported. Conclusions: This study found that AOM is associated with some negative impact on parental QoL and significant economic impact at both patient and societal levels. The findings provide useful data on healthcare resource utilization and disease burden of AOM in Malaysia. Adis Open Access 2017 Article PeerReviewed Crawford, Bruce and Hashim, Siti Sabzah Mohd and Prepageran, Narayanan and Goh, Bee See and Meier, Genevieve and Wada, Keiko and Coon, Cheryl and Delgleize, Emmanuelle and DeRosa, Michael (2017) Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study. Drugs - Real World Outcomes, 4 (1). pp. 21-31. ISSN 2199-1154 http://dx.doi.org/10.1007/s40801-016-0099-9 doi:10.1007/s40801-016-0099-9
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Crawford, Bruce
Hashim, Siti Sabzah Mohd
Prepageran, Narayanan
Goh, Bee See
Meier, Genevieve
Wada, Keiko
Coon, Cheryl
Delgleize, Emmanuelle
DeRosa, Michael
Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study
description Background: Acute otitis media (AOM) affects both child and parental quality of life (QoL). Data on QoL associated with AOM in Malaysia is sparse, and the burden of indirect costs have not been previously reported. Objective: To determine the effect of pediatric AOM on child and parental QoL in Malaysia and its economic impact (indirect costs). Methods: We utilized a set of QoL questionnaires (PAR-AOM-QOL, OM-6, and EQ-5D) combined with questions addressing work/productivity loss and financial costs associated with caring for a child during his or her illness in an observational, multicenter, prospective study. Results: One hundred and ten AOM patients aged ≤5 years were included in the analysis. The majority of respondents were the patient’s mother. Parental QoL was negatively affected for both emotional and daily disturbance scales, but the level of disturbance was low. Using OM-6, the greatest negative impact was on the child’s QoL, followed by caregiver concerns, physical suffering, and emotional distress. Using EQ-5D, a moderately positive relationship between parents’ emotional disturbance and daily disturbance, and a weak, negative correlation between parental emotional disturbance and parental health status was found. Parents with paid employment took an average of 21 h from work to care for their child, at an average cost of 321.8 Malaysian ringgit (US$97) in addition to their contribution to direct medical costs. Productivity losses whilst at work, uncompensated wage losses, and leisure time losses are also reported. Conclusions: This study found that AOM is associated with some negative impact on parental QoL and significant economic impact at both patient and societal levels. The findings provide useful data on healthcare resource utilization and disease burden of AOM in Malaysia.
format Article
author Crawford, Bruce
Hashim, Siti Sabzah Mohd
Prepageran, Narayanan
Goh, Bee See
Meier, Genevieve
Wada, Keiko
Coon, Cheryl
Delgleize, Emmanuelle
DeRosa, Michael
author_facet Crawford, Bruce
Hashim, Siti Sabzah Mohd
Prepageran, Narayanan
Goh, Bee See
Meier, Genevieve
Wada, Keiko
Coon, Cheryl
Delgleize, Emmanuelle
DeRosa, Michael
author_sort Crawford, Bruce
title Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study
title_short Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study
title_full Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study
title_fullStr Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study
title_full_unstemmed Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study
title_sort impact of pediatric acute otitis media on child and parental quality of life and associated productivity loss in malaysia: a prospective observational study
publisher Adis Open Access
publishDate 2017
url http://eprints.um.edu.my/19198/
http://dx.doi.org/10.1007/s40801-016-0099-9
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