Characterization and potential roles of bone marrow-derived stromal cells in cancer development and metastasis

• Main Authors: Kawai, Hotaka, Tsujigiwa, Hidetsugu, Siar, Chong Huat, Nakano, Keisuke, Takabatake, Kiyofumi, Fujii, Masae, Hamada, Mei, Tamamura, Ryo, Nagatsuka, Hitoshi
• Format: Article
• Language: English
• Published: Ivyspring International Publisher 2018
• Subjects: RK Dentistry; Oral surger
• Online Access: http://eprints.um.edu.my/19804/1/v15p1406.pdf; http://eprints.um.edu.my/19804/; http://www.medsci.org/v15p1406.htm
• Institution: Universiti Malaya

Background: The tumor microenvironment and its stromal cells play an important role in cancer development and metastasis. Bone marrow-derived cells (BMDCs), a rich source of hematopoietic and mesenchymal stem cells, putatively contribute to this tumoral stroma. However their characteristics and role...