Anti-ulcerogenic activity of dentatin from clausena excavata Burm.f. against ethanol-induced gastric ulcer in rats: Possible role of mucus and anti-oxidant effect

• Main Authors: Sidahmed, Heyam Mohamed Ali, Vadivelu, Jamuna, Loke, Mun Fai, Arbab, Ismail Adam, Abdul, Bustamam, Sukari, Mohd Aspollah, Abdelwahab, Siddig Ibrahim
• Format: Article
• Published: Elsevier 2019
• Subjects: Q Science (General); QD Chemistry; R Medicine
• Online Access: http://eprints.um.edu.my/19991/; https://doi.org/10.1016/j.phymed.2018.06.036
• Institution: Universiti Malaya

Background: Clausena excavata Burm.f. (Rutaceae) has been used for the treatment of stomach disorders including peptic ulcer. Purpose: In this study, we aimed to investigate dentatin isolated from C. excavata Burm.f., for anti-ulcer activity against ethanol ulcer model in rats. Methods: Gastric acid...