Cytotoxic Effects of Pinnatane A Extracted from Walsura pinnata (Meliaceae) on Human Liver Cancer Cells

• Main Authors: Zakaria, Nurhisyam, Mahdzir, Mohamad, Yusoff, Mahfuzah, Arshad, Norhafiza Mohd, Awang, Khalijah, Nagoor, Noor Hasima
• Format: Article
• Published: MDPI 2018
• Subjects: Q Science (General); QD Chemistry; QH Natural history
• Online Access: http://eprints.um.edu.my/20186/; https://doi.org/10.3390/molecules23112733
• Institution: Universiti Malaya

Background: Pinnatane A from the bark of Walsura pinnata was investigated for its anti-cancer properties by analyzing the cytotoxic activities and cell cycle arrest mechanism induced in two different liver cancer cell lines. Methods: A 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide...