Molecular attributes and apoptosis-inducing activities of a putative serine protease isolated from Tiger Milk mushroom (Lignosus rhinocerus) sclerotium against breast cancer cells in vitro

• Main Authors: Yap, Hui Yeng Yeannie, Tan, Nget Hong, Ng, Szu Ting, Tan, Chon Seng, Fung, Shin Yee
• Format: Article
• Published: PeerJ 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/20316/; https://doi.org/10.7717/peerj.4940
• Institution: Universiti Malaya

Background: The highly valued medicinal tiger milk mushroom (also known as Lignosus rhinocerus) has the ability to cure numerous ailments. Its anticancer activities are well explored, and recently a partially purified cytotoxic protein fraction termed F5 from the mushroom's sclerotial cold wate...