T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses

T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses

T-cell exhaustion is a phenomenon of dysfunction or physical elimination of antigen-specific T cells reported in human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) infections as well as cancer. Exhaustion appears to be often restricted to CD8+ T cells responses...

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Main Authors: Saeidi, Alireza, Zandi, Keivan, Cheok, Yi Ying, Saeidi, Hamidreza, Wong, Won Fen, Lee, Chalystha Yie Qin, Cheong, Heng Choon, Yong, Yean Kong, Larsson, Marie, Shankar, Esaki Muthu
Format: Article
Published: Frontiers Media 2018
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/20831/
https://doi.org/10.3389/fimmu.2018.02569
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Institution: Universiti Malaya

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http://eprints.um.edu.my/20831/
https://doi.org/10.3389/fimmu.2018.02569

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