Cycloartane Triterpenoids with Anti-melanin Deposition Activity

• Main Authors: Nugroho, Alfarius Eko, Matsumoto, Misaki, Sotozono, Yayoi, Kaneda, Toshio, A. Hadi, A. Hamid, Morita, Hiroshi
• Format: Article
• Published: SAGE Publications 2018
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/21095/; https://doi.org/10.1177/1934578X1801300706
• Institution: Universiti Malaya

Bioactivity guided separation of the extract of Malaysian Garcinia sp. resulted in the isolation of 23-acetoxy-mangiferonic acid (1) and the absolute configuration of C-23 was elucidated to be R by the advanced Mosher's method. The anti-melanin deposition activity of 1 was caused by the down re...