Synthesis of 1,3-benzoxazines Based on 2,4,4-trimethyl-7,2’,4’-trihydroxy Flavan: Antibacterial, Anti-inflammatory, Cyclooxygenase-2 Inhibition and Molecular Modelling Studies
Background: In the present study, the formation of 2, 4, 4-trimethyl-7,2’4’-trihydroxy flavan has been used as the key feature for the formation of new 1,3-benzoxazines. This reaction was carried out via Mannich-condensation reaction, the 7-hydroxy group of flavan was reacted with different primary...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Bentham Science Publishers
2018
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/21246/ https://doi.org/10.2174/1570180815666180420100922 |
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| Institution: | Universiti Malaya |