Rosiglitazone diminishes the high-glucose-induced modulation of 5-fluorouracil cytotoxicity in colorectal cancer cells

• Main Authors: Lau, Meng Fei, Vellasamy, Shalini, Chua, Kek Heng, Sabaratnam, Vikineswary, Kuppusamy, Umah Rani
• Format: Article
• Published: Leibniz Research Centre for Working Environment and Human Factors 2018
• Subjects: Q Science (General); QH Natural history; R Medicine
• Online Access: http://eprints.um.edu.my/21546/; https://www.excli.de/vol17/Kuppusamy_06022018_proof.pdf
• Institution: Universiti Malaya

Colorectal cancer (CRC) is the third most leading cause of morbidity and mortality throughout the world. 5-fluorouracil (5-FU), which is often administrated to disrupt carcinogenesis, was found to elevate blood glucose level among CRC patients. Thus, this study was conducted to evaluate the influenc...