STK15 Phe31Ile and Val57Ile Polymorphisms Increase the Risk of Gastrointestinal Cancer

• Main Authors: Lai, Tianxin, Chong, Eric Tzyy Jiann, Chuah, Jitt Aun, Chua, Kek Heng, Lee, Ping Chin
• Format: Article
• Published: Penerbit Universiti Kebangsaan Malaysia 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/21554/; https://doi.org/10.17576/jsm-2018-4701-17
• Institution: Universiti Malaya

STK15 is a serine/threonine kinase that regulates chromosomal segregation during mitosis. Single nucleotide polymorphisms (SNPs) in this gene, Phe31Ile (rs2273535) and Val57Ile (rs1047972), are inconsistently associated with gastrointestinal cancer (GIC) across different populations. However, this a...