Paeonol Attenuates LPS-Induced Endothelial Dysfunction and Apoptosis by Inhibiting BMP4 and TLR4 Signaling Simultaneously but Independently

Paeonol Attenuates LPS-Induced Endothelial Dysfunction and Apoptosis by Inhibiting BMP4 and TLR4 Signaling Simultaneously but Independently

Inflammatory injury of the endothelium leads to apoptosis and endothelial dysfunction. The current study explored the effect and mechanisms of paeonol in inflammation-induced apoptosis and endothelial dysfunction induced by lipopolysaccharides (LPSs). The effects of paeonol on LPS-induced inflammato...

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Bibliographic Details
Main Authors: Choy, Ker Woon, Lau, Yeh Siang, Murugan, Dharmani Devi, Vanhoutte, Paul M., Mustafa, Mohd Rais
Format: Article
Published: American Society for Pharmacology and Experimental Therapeutics 2017
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/22189/
https://doi.org/10.1124/jpet.117.245217
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Institution: Universiti Malaya

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http://eprints.um.edu.my/22189/
https://doi.org/10.1124/jpet.117.245217

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