Long-term exposure to insulin and volumetric mammographic density: observational and genetic associations in the Karma study

• Main Authors: Borgquist, Signe, Rosendahl, Ann H., Czene, Kamila, Bhoo-Pathy, Nirmala, Dorkhan, Mozhgan, Hall, Per, Brand, Judith S.
• Format: Article
• Published: BMC 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/22301/; https://doi.org/10.1186/s13058-018-1026-7
• Institution: Universiti Malaya

Background: Long-term insulin exposure has been implicated in breast cancer etiology, but epidemiological evidence remains inconclusive. The aims of this study were to investigate the association of insulin therapy with mammographic density (MD) as an intermediate phenotype for breast cancer and to...