Brain Lipopolysaccharide Preconditioning-Induced Gene Reprogramming Mediates a Tolerance State in Electroconvulsive Shock Model of Epilepsy

• Main Authors: Amini, Elham, Golpich, Mojtaba, Farjam, Abdoreza S., Kamalidehghan, Behnam, Mohamed, Zahurin, Ibrahim, Norlinah M., Ahmadiani, Abolhassan, Raymond, Azman A.
• Format: Article
• Published: Frontiers Media 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/22501/; https://doi.org/10.3389/fphar.2018.00416
• Institution: Universiti Malaya

There is increasing evidence pointing toward the role of inflammatory processes in epileptic seizures, and reciprocally, prolonged seizures induce more inflammation in the brain. In this regard, effective strategies to control epilepsy resulting from neuroinflammation could be targeted. Based on the...