Within-population genetic diversity and population structure of Plasmodium knowlesi merozoite surface protein 1 gene from geographically distinct regions of Malaysia and Thailand

• Main Authors: Ahmed, Md Atique, Chu, Ki Back, Vythilingam, Indra, Quan, Fu-Shi
• Format: Article
• Published: BioMed Central 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/22625/; https://doi.org/10.1186/s12936-018-2583-z
• Institution: Universiti Malaya

Background: The C-terminal 42 kDa domain of Plasmodium knowlesi merozoite surface protein 1 (PkMSP1) is a potential asexual blood-stage vaccine candidate, however, only a limited number of clinical isolates have been analysed from Malaysia and no inter-country comparative diversity study has been co...