AnkPlex: algorithmic structure for refinement of near-native ankyrin-protein docking

• Main Authors: Wisitponchai, Tanchanok, Shoombuatong, Watshara, Lee, Vannajan Sanghiran, Kitidee, Kuntida, Tayapiwatana, Chatchai
• Format: Article
• Published: BioMed Central 2017
• Subjects: Q Science (General); QD Chemistry; R Medicine
• Online Access: http://eprints.um.edu.my/22804/; https://doi.org/10.1186/s12859-017-1628-6
• Institution: Universiti Malaya

Background: Computational analysis of protein-protein interaction provided the crucial information to increase the binding affinity without a change in basic conformation. Several docking programs were used to predict the near-native poses of the protein-protein complex in 10 top-rankings. The unive...