Chitosan complexed carboxymethylated iota-carrageenan oral insulin particles: Stability, permeability and in vivo evaluation

We previously reported that insulin-entrapped chitosan complexed carboxymethylated iota-carrageenan (CS/CMCi) particles exhibit pH-responsive swelling behavior. However, the particles’ stability in the enzymatic gastrointestinal environment, their drug permeability mechanism, and related in vivo stu...

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Bibliographic Details
Main Authors: Sahoo, Pratyusa, Leong, Kok Hoong, Nyamathulla, Shaik, Onuki, Yoshinori, Takayama, Kozo, Chung, Lip Yong
Format: Article
Published: Elsevier 2019
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Online Access:http://eprints.um.edu.my/23586/
https://doi.org/10.1016/j.mtcomm.2019.100557
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Institution: Universiti Malaya
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