Small molecule grp94 inhibitors block dengue and Zika virus replication
Two major flaviviruses, dengue virus (DENV) and Zika virus (ZIKV), cause severe health and economic burdens worldwide. Recently, genome-wide screenings have uncovered the importance of regulators of the Hrd1 ubiquitin ligase-mediated endoplasmic reticulum (ER)-associated degradation (ERAD) pathway f...
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Main Authors: | , , , , , , , , |
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Format: | Article |
Published: |
Elsevier Masson
2019
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Subjects: | |
Online Access: | http://eprints.um.edu.my/23623/ https://doi.org/10.1016/j.antiviral.2019.104590 |
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Institution: | Universiti Malaya |