Biophysical and computational approaches to unravel the molecular interaction mechanism of bromodeoxyuridine, a proliferative marker with human serum albumin
Abstract: The interaction of a nucleoside analogue bromodeoxyuridine (BrdU) with human serum albumin (HSA) was studied to investigate the binding phenomenon and analyse the protein conformation upon BrdU binding. Multiple spectroscopic techniques, viz. intrinsic and 3-D fluorescence, UV–Vis absorpti...
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Main Authors: | , , , , |
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Format: | Article |
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Springer Verlag
2019
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Subjects: | |
Online Access: | http://eprints.um.edu.my/23633/ https://doi.org/10.1007/s00706-019-02518-z |
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Institution: | Universiti Malaya |