Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not?

Background: Some oral verrucal lesions may constitute parts of the clinicopathological spectrum of proliferative verrucous leukoplakia (PVL). Because of its idiopathic yet sinister nature, it is possible that PVL may exist in other populations. The aim of this study was to review the clinicopatholog...

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Main Authors: Zain, R.B., Ghazali, N., Bakri, M.M.
Format: Article
Language:English
Published: 2003
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Online Access:http://eprints.um.edu.my/2364/1/Aggressive_multifocal_oral_verrucous_leukoplakia_Proliferative_verrucous_leukoplakia_or_not.pdf
http://eprints.um.edu.my/2364/
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spelling my.um.eprints.23642014-10-20T01:46:22Z http://eprints.um.edu.my/2364/ Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not? Zain, R.B. Ghazali, N. Bakri, M.M. R Medicine RB Pathology RK Dentistry Background: Some oral verrucal lesions may constitute parts of the clinicopathological spectrum of proliferative verrucous leukoplakia (PVL). Because of its idiopathic yet sinister nature, it is possible that PVL may exist in other populations. The aim of this study was to review the clinicopathological features of persistent, multifocal, oral verrucal lesions in Malaysian population. Methods: Patients with multifocal oral verrucal lesions were selected from surgical and histopathological records. Results: Nine patients of diverse ethnicity with 43 biopsies were reviewed. The mean age at the presentation was 62 years. The most frequent sites affected were gum, sulci, cheek and tongue. Indulgence in risk habits was reported in about 70% of patients. Four cases developed multifocal carcinoma from multifocal leukoplakia. Conclusions: In retrospect, none of the cases fulfilled the original PVL criteria, although three cases were suggestive of PVL. Nevertheless, these findings do not necessarily preclude the existence of PVL as a clinicopathological entity in Malaysian population. 2003-08 Article PeerReviewed application/pdf en http://eprints.um.edu.my/2364/1/Aggressive_multifocal_oral_verrucous_leukoplakia_Proliferative_verrucous_leukoplakia_or_not.pdf Zain, R.B. and Ghazali, N. and Bakri, M.M. (2003) Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not? Journal of Oral Pathology and Medicine, 32 (7). pp. 383-392. ISSN 0904-2512 10.1034/j.1600-0714.2003.00180.x
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic R Medicine
RB Pathology
RK Dentistry
spellingShingle R Medicine
RB Pathology
RK Dentistry
Zain, R.B.
Ghazali, N.
Bakri, M.M.
Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not?
description Background: Some oral verrucal lesions may constitute parts of the clinicopathological spectrum of proliferative verrucous leukoplakia (PVL). Because of its idiopathic yet sinister nature, it is possible that PVL may exist in other populations. The aim of this study was to review the clinicopathological features of persistent, multifocal, oral verrucal lesions in Malaysian population. Methods: Patients with multifocal oral verrucal lesions were selected from surgical and histopathological records. Results: Nine patients of diverse ethnicity with 43 biopsies were reviewed. The mean age at the presentation was 62 years. The most frequent sites affected were gum, sulci, cheek and tongue. Indulgence in risk habits was reported in about 70% of patients. Four cases developed multifocal carcinoma from multifocal leukoplakia. Conclusions: In retrospect, none of the cases fulfilled the original PVL criteria, although three cases were suggestive of PVL. Nevertheless, these findings do not necessarily preclude the existence of PVL as a clinicopathological entity in Malaysian population.
format Article
author Zain, R.B.
Ghazali, N.
Bakri, M.M.
author_facet Zain, R.B.
Ghazali, N.
Bakri, M.M.
author_sort Zain, R.B.
title Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not?
title_short Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not?
title_full Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not?
title_fullStr Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not?
title_full_unstemmed Aggressive, multifocal oral verrucous leukoplakia: Proliferative verrucous leukoplakia or not?
title_sort aggressive, multifocal oral verrucous leukoplakia: proliferative verrucous leukoplakia or not?
publishDate 2003
url http://eprints.um.edu.my/2364/1/Aggressive_multifocal_oral_verrucous_leukoplakia_Proliferative_verrucous_leukoplakia_or_not.pdf
http://eprints.um.edu.my/2364/
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