Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations

Radiation dose exposure in computed tomography (CT) is acknowledged higher when compared to other imaging modalities. The side effects on children have always been a considerable concern. This retrospective study evaluated the dose exposure and organ cancer risk in paediatric patients who underwent...

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Main Authors: Muhammad, N.A., Karim, Muhammad Khalis Abdul, Hassan, Hasyma Abu, Kamarudin, Mazliana Ahmad, Wong, Jeannie Hsiu Ding, Ibahim, Mohammad Johari
Format: Article
Published: Elsevier 2019
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Online Access:http://eprints.um.edu.my/23944/
https://doi.org/10.1016/j.radphyschem.2019.108438
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spelling my.um.eprints.239442020-03-04T00:53:02Z http://eprints.um.edu.my/23944/ Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations Muhammad, N.A. Karim, Muhammad Khalis Abdul Hassan, Hasyma Abu Kamarudin, Mazliana Ahmad Wong, Jeannie Hsiu Ding Ibahim, Mohammad Johari QC Physics R Medicine Radiation dose exposure in computed tomography (CT) is acknowledged higher when compared to other imaging modalities. The side effects on children have always been a considerable concern. This retrospective study evaluated the dose exposure and organ cancer risk in paediatric patients who underwent CT thorax-abdomen-pelvis (CT TAP) between January 2016 and December 2018. The records of 34 boys and 39 girls (n = 73) were retrieved and divided into three age groups (0–4, 5–9 and 10–12) — the standard protocol for helical scanning setup at 100 kV and 210 mAs. Generally, the CT dose index volume, dose length product and effective dose increased in tandem with the children's age due to higher body mass index. From the youngest to the oldest age group, the liver had the highest cancer risk, especially for boys, which was most likely due to its anatomical location in the scan area. However, from age 5 and above, steep increments were observed in the risk for ovaries, whereas testicles had none. Thus, it is recommended to take precautions when subjecting children to CT TAP, especially prepubescent girls, whose ovaries exposed to almost a thousand times cancer risk per 100,000 procedure. © 2019 Elsevier Ltd Elsevier 2019 Article PeerReviewed Muhammad, N.A. and Karim, Muhammad Khalis Abdul and Hassan, Hasyma Abu and Kamarudin, Mazliana Ahmad and Wong, Jeannie Hsiu Ding and Ibahim, Mohammad Johari (2019) Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations. Radiation Physics and Chemistry, 165. p. 108438. ISSN 0969-806X https://doi.org/10.1016/j.radphyschem.2019.108438 doi:10.1016/j.radphyschem.2019.108438
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic QC Physics
R Medicine
spellingShingle QC Physics
R Medicine
Muhammad, N.A.
Karim, Muhammad Khalis Abdul
Hassan, Hasyma Abu
Kamarudin, Mazliana Ahmad
Wong, Jeannie Hsiu Ding
Ibahim, Mohammad Johari
Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations
description Radiation dose exposure in computed tomography (CT) is acknowledged higher when compared to other imaging modalities. The side effects on children have always been a considerable concern. This retrospective study evaluated the dose exposure and organ cancer risk in paediatric patients who underwent CT thorax-abdomen-pelvis (CT TAP) between January 2016 and December 2018. The records of 34 boys and 39 girls (n = 73) were retrieved and divided into three age groups (0–4, 5–9 and 10–12) — the standard protocol for helical scanning setup at 100 kV and 210 mAs. Generally, the CT dose index volume, dose length product and effective dose increased in tandem with the children's age due to higher body mass index. From the youngest to the oldest age group, the liver had the highest cancer risk, especially for boys, which was most likely due to its anatomical location in the scan area. However, from age 5 and above, steep increments were observed in the risk for ovaries, whereas testicles had none. Thus, it is recommended to take precautions when subjecting children to CT TAP, especially prepubescent girls, whose ovaries exposed to almost a thousand times cancer risk per 100,000 procedure. © 2019 Elsevier Ltd
format Article
author Muhammad, N.A.
Karim, Muhammad Khalis Abdul
Hassan, Hasyma Abu
Kamarudin, Mazliana Ahmad
Wong, Jeannie Hsiu Ding
Ibahim, Mohammad Johari
author_facet Muhammad, N.A.
Karim, Muhammad Khalis Abdul
Hassan, Hasyma Abu
Kamarudin, Mazliana Ahmad
Wong, Jeannie Hsiu Ding
Ibahim, Mohammad Johari
author_sort Muhammad, N.A.
title Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations
title_short Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations
title_full Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations
title_fullStr Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations
title_full_unstemmed Estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – Abdomen - Pelvis examinations
title_sort estimation of effective dose and organ cancer risk from paediatric computed tomography thorax – abdomen - pelvis examinations
publisher Elsevier
publishDate 2019
url http://eprints.um.edu.my/23944/
https://doi.org/10.1016/j.radphyschem.2019.108438
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