Effect of acidosis on the mechanism (s) of insulin-induced vasorelaxation in normal Wistar-Kyoto (WKY) rat aorta

The effect of acidosis on insulin-induced relaxation was studied in thoracic aortic rings (from Wistar–Kyoto (WKY) rats) with (+ED) or without (−ED) endothelium. The rings were mounted in normal (pH 7.4) or acidotic (pH 7.2) Krebs solution for isometric tension recording. Phenylephrine (PE, 3.0 µM...

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Bibliographic Details
Main Authors: Subramaniam, G., Achike, F.I., Mustafa, Mohd Rais
Format: Article
Language:English
Published: Elsevier 2009
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Online Access:http://eprints.um.edu.my/2417/1/Effect_of_acidosis_on_the_mechanism_%28s%29_of_insulin-induced_vasorelaxation_in_normal_Wistar-Kyoto_%28WKY%29_rat_aorta.pdf
http://eprints.um.edu.my/2417/
http://www.sciencedirect.com/science/journal/01670115
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Institution: Universiti Malaya
Language: English