Dengue 2: (New guinea C strain) virus infection induces apoptosis

The ability of dengue 2 virus infection to induce apoptosis was investigated. Dengue 2 virus-infected African green monkey kidney cells {Vera}. showed the presence of about 2. 9'. 22 and 30 percent apoptotic cells on day 3. S. B. and 11 postinfection. respectively. Increased number of apoptotic...

Full description

Saved in:
Bibliographic Details
Main Authors: Shafee, Norazizah, AbuBakar, Sazaly
Format: Article
Published: Faculty of Medicine, University of Malaya 1997
Subjects:
Online Access:http://eprints.um.edu.my/24377/
https://jummec.um.edu.my/article/view/4399
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universiti Malaya
Description
Summary:The ability of dengue 2 virus infection to induce apoptosis was investigated. Dengue 2 virus-infected African green monkey kidney cells {Vera}. showed the presence of about 2. 9'. 22 and 30 percent apoptotic cells on day 3. S. B. and 11 postinfection. respectively. Increased number of apoptotic cells corresponded with increasing number of dengue 2 antigen positive cells. Induction of internucleosomal DNA fragmentation. characteristic of apoptotic cells, was noted also in dengue 2 virus-infected mosquito cell (C6f36) cultures. These results suggested that dengue 2 virus infection in nitro stimulated apoptotic cellular responses.