The use of mycophenolate mofetil in treating patients with non responding aplastic anemia

Aplastic anemia is a relatively uncommon disease and conventional management options include immunosuppressive drugs and/or haematopoeitic stem cell transplantation. It is now known that the pathogenesis of aplastic anemia is immune mediated. Mycophenolate mofetil is a common immunosuppressive drug...

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Main Authors: Gan, Gin Gin, Leong, C.F., Sangkar, J.V., Teh, A., Goh, K.Y., Cheong, S.K.
Format: Article
Language:English
Published: Malaysian Medical Association 2005
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Online Access:http://eprints.um.edu.my/24590/1/Aplastic_Anemia.pdf
http://eprints.um.edu.my/24590/
http://www.e-mjm.org/2005/v60n3/Aplastic_Anemia.pdf
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spelling my.um.eprints.245902020-06-03T06:58:22Z http://eprints.um.edu.my/24590/ The use of mycophenolate mofetil in treating patients with non responding aplastic anemia Gan, Gin Gin Leong, C.F. Sangkar, J.V. Teh, A. Goh, K.Y. Cheong, S.K. R Medicine Aplastic anemia is a relatively uncommon disease and conventional management options include immunosuppressive drugs and/or haematopoeitic stem cell transplantation. It is now known that the pathogenesis of aplastic anemia is immune mediated. Mycophenolate mofetil is a common immunosuppressive drug now used mainly in prophylaxis of graft rejection in organ transplant and also for prevention/treatment for graft versus host disease in haemtopoeitic stem cell transplantation. It is thought that mycophenolate mofetil may be useful in this group of patients. In this short report, mycophenolate mofetil was tried in 6 patients who had severe aplastic anemia with variable doses for a minimum duration of 9 months. The result has however not been encouraging. Malaysian Medical Association 2005 Article PeerReviewed text en http://eprints.um.edu.my/24590/1/Aplastic_Anemia.pdf Gan, Gin Gin and Leong, C.F. and Sangkar, J.V. and Teh, A. and Goh, K.Y. and Cheong, S.K. (2005) The use of mycophenolate mofetil in treating patients with non responding aplastic anemia. Medical Journal of Malaysia, 60 (3). pp. 311-313. ISSN 0300-5283 http://www.e-mjm.org/2005/v60n3/Aplastic_Anemia.pdf
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic R Medicine
spellingShingle R Medicine
Gan, Gin Gin
Leong, C.F.
Sangkar, J.V.
Teh, A.
Goh, K.Y.
Cheong, S.K.
The use of mycophenolate mofetil in treating patients with non responding aplastic anemia
description Aplastic anemia is a relatively uncommon disease and conventional management options include immunosuppressive drugs and/or haematopoeitic stem cell transplantation. It is now known that the pathogenesis of aplastic anemia is immune mediated. Mycophenolate mofetil is a common immunosuppressive drug now used mainly in prophylaxis of graft rejection in organ transplant and also for prevention/treatment for graft versus host disease in haemtopoeitic stem cell transplantation. It is thought that mycophenolate mofetil may be useful in this group of patients. In this short report, mycophenolate mofetil was tried in 6 patients who had severe aplastic anemia with variable doses for a minimum duration of 9 months. The result has however not been encouraging.
format Article
author Gan, Gin Gin
Leong, C.F.
Sangkar, J.V.
Teh, A.
Goh, K.Y.
Cheong, S.K.
author_facet Gan, Gin Gin
Leong, C.F.
Sangkar, J.V.
Teh, A.
Goh, K.Y.
Cheong, S.K.
author_sort Gan, Gin Gin
title The use of mycophenolate mofetil in treating patients with non responding aplastic anemia
title_short The use of mycophenolate mofetil in treating patients with non responding aplastic anemia
title_full The use of mycophenolate mofetil in treating patients with non responding aplastic anemia
title_fullStr The use of mycophenolate mofetil in treating patients with non responding aplastic anemia
title_full_unstemmed The use of mycophenolate mofetil in treating patients with non responding aplastic anemia
title_sort use of mycophenolate mofetil in treating patients with non responding aplastic anemia
publisher Malaysian Medical Association
publishDate 2005
url http://eprints.um.edu.my/24590/1/Aplastic_Anemia.pdf
http://eprints.um.edu.my/24590/
http://www.e-mjm.org/2005/v60n3/Aplastic_Anemia.pdf
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